The overall HST Connect project is one of the most comprehensive transnational partnership projects, involving the majority of NWE member states, a wide range of regional government partners and an impressive list of local investment partners. The project partnership also works closely with respective rail agencies and transport operators.

The following partners are directly involved in the HST Connect partnership:

• The South East England Development Agency (SEEDA, Lead Partner, UK)
• Reading Borough Council (UK)
• Seaspace Ltd (UK)
• Kent County Council (UK)
• Government Office for the South East (UK)
• Région Nord-Pas de Calais (FR)
• Leiedal Intercommunale voor Streek Ontwikkeling (B)
• Provincie West-Vlaanderen (B)
• Ville de Liège (B)
• Gemeente Maastricht (NL)
• Lille Métropole Communauté Urbaine (FR)
• City of Aachen (D)
• Gemeente Eindhoven (NL)
• South East England Regional Assembly (SEERA, UK)
• Strategic Rail Authority (UK)